Department of Human Genetics

Anthony Antonellis
Assistant Professor of Human Genetics
Assistant Professor of Neurology
3710A Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-647-4058
Fax: 734-763-3784
Email: antonell@umich.edu
Research:
Identify and characterize loci involved in axonal and demyelinating peripheral neuropathies.

David T. Burke
Professor of Human Genetics
Associate Research Scientist for Institute of Gerontology
5815 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-647-3149
Fax: 734-763-3784
Email: dtburke@umich.edu
Research:
Molecular and quantitative genetics of mammalian aging; microfabricated nucleic acids analysis technology.

Margit Burmeister
Professor of Human GeneticsProfessor of Psychiatry Research Professor, Molecular & Behavioral Neuroscience Institute
5061 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-647-2186
Fax: 734-936-2690
Email: margit@umich.edu
Research:
Identification of genes involved in behavior, and neurological and psychiatric disorders.

Sally A. Camper
James V. Neel Professor and Chair, Department of Human Genetics
Professor, Department of Internal Medicine
4945 Buhl
1241 E Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-763-0682
Fax: 734-763-5831
Email: scamper@umich.edu
Research:
Development and function of the neuroendocrine, skeletal, and auditory system using transgenic mice, gene targeting, and molecular genetic analysis of mouse and human mutations.

Raymond C. Chan
Assistant Professor of Human Genetics
Assistant Professor of Internal Medicine-MMG
5814 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-615-5393
Fax: 734-763-3784
Email: rchan@umich.edu
Research:
Our lab focuses on how the Structural Maintenance of Chromosomes (SMC) proteins mediate higher-order chromosome organization necessary for accurate chromosome segregation and efficient DNA repair.

Ernest Chu
Professor Emeritus of Human Genetics
4909 Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-647-3149
Fax: 734-763-3784
Email: ernestch@umich.edu

Julie A. Douglas
Associate Professor of Human Genetics
5912 Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor , MI 48109 -5618
Phone: 734-615-2616
Fax: 734-763-3784
Email: jddoug@umich.edu
Research:
Statistical genetics, genetic epidemiology, and cancer genetics. Current efforts in my lab focus on the design of human, population-based genetic studies and the application and development of statistical genetic methods to identify genes underlying predisposition to hormonally sensitive cancers (including those of the breast and prostate) and variation in related, intermediate quantitative traits such as breast density, an established risk factor for breast cancer.

Eric R Fearon
Emanuel N. Maisel Professor of Oncology
Professor of Internal Medicine
Professor of Pathology
Professor of Human Genetics
1504 BSRB, Box 2200
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-764-1549
Fax: 734-647-7950
Email: fearon@umich.edu
Research:
Our research is focused on the means by which genetic and epigenetic alterations in selected signal transduction pathways contribute to cancer pathogenesis.

Thomas D. Gelehrter
Emeritus Professor of Human Genetics
Professor of Internal Medicine
5718A Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-936-2860
Fax: 734-763-3784
Email: tdgum@umich.edu
Research:
Transcriptional and posttranscriptional regulation of gene expression by hormones, cytokines, and growth factors.

David Ginsburg
Investigator, Howard Hughes Medical Institute
James V Neel Distinguished University Professor Internal Medicine & Human Genetics
Research Professor, Life Sciences Institute
Warner-Lambert/Parke-Davis Professor of Medicine
5028 LSI
210 Washtenaw
Ann Arbor , MI 48109 -2216
Phone: 734-647-4808
Fax: 734-936-2888
Email: ginsburg@umich.edu
Research:
The Ginsburg lab is interested in understanding the components of the blood-clotting system and how disturbances in their function lead to human bleeding and blood-clotting disorders.

Thomas M. Glaser
Associate Professor, Human Genetics Department
Associate Professor, Internal Medicine Department
2047 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-764-4580
Fax: 734-763-2162
Email: tglaser@umich.edu
Research:
Mouse and human developmental genetics. Visual system development and function, retinal cell fate determination, ribosomal protein disorders and tissue growth control.

Thomas W. Glover
Professor of Human Genetics; Professor of Pediatrics and Communicable Diseases
4718A Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-763-5222
Fax: 734-763-3784
Email: glover@umich.edu
Research:
Mechanisms and consequences of genome instability with focus on chromosome fragile sites; molecular basis of human genetic disorders including hereditary lymphedema and Hutchinson-Gilford progeria.

Stephen B. Gruber
Professor of Human Genetics
Professor of the Epidemiology Department
Professor of Internal Medicine
1524 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-615-9712
Fax: 734-763-7672
Email: sgruber@umich.edu
Research:
Translational cancer genetics, focusing on the genetic epidemiology of colorectal cancer and melanoma. Molecular epidemiology, gene environment interactions, whole genome association studies.

Friedhelm Hildebrandt
Investigator, Howard Hughes Medical Institute
Professor of Pediatrics
Professor of Human Genetics
Frederick G. L. Huetwell Professor for the Cure and Prevention of Birth Defects
Doris Duke Distinguished Clinical Scientist
8220C MSRB III
1150 W. Medical Center Drive
Ann Arbor, MI 48109 -646
Phone: 734-615-7285
Fax: 734-615-1386
Email: fhilde@umich.edu
Research:
Our research focuses on positional cloning of genes causing kidney diseases, such as cystic kidney diseases, nephronophthisis, urinary tract malformations, nephrotic syndrome, and Bartter syndrome. We also study the molecular genetics and functional aspects of developmental defects of kidney, eye and auditory system. Animal models for genetic kidney diseases are generated for novel genes identified.

Jeffrey W. Innis
Professor of Human Genetics
Professor of Pediatrics and Communicable Diseases
Division Director, Pediatric Genetics
Director, Michigan Medical Genetics Laboratories
Director, ABMG Training Programs
4811 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-647-3817
Fax: 734-763-3784
Email: innis@umich.edu
Research:
Genetics of human and mouse limb malformation syndromes; Hox genes and limb development; target genes of Hox proteins; Hox genes and development of the chorioallantoic placenta.

Sundeep Kalantry
Assistant Professor of Human Genetics
3710-C Med Sci II
1241 E. Catherine St.
Ann Arbor, MI 48109 -5618
Phone: 734-615-9578
Fax: 734-763-3784
Email: kalantry@umich.edu
Research:
Our research aims to define the epigenetic mechanisms that regulate X-chromosome inactivation, which results in transcriptional silencing of most genes along one of the two X-chromosomes in female mammals. We utilize mouse models and various stem cell lines derived from the early mouse embryo in our studies.

Please see the lab website for additional details.

Catherine Keegan
Assistant Professor of Pediatrics
Assistant Professor of Human Genetics
3520 MSRB I SPC 5652
1150 W. Medical Center Drive
Ann Arbor, MI 48109
Phone: 734-647-8237
Fax: 734-763-6561
Email: keeganc@umich.edu
Research:
The focus of the research in my laboratory is to understand the developmental pathways that are required for formation of the caudal portion of the embryo and the mechanisms that lead to birth defects affecting caudal structures in humans.

John K. Kim
Assistant Professor of Human Genetics
Assistant Research Professor, Life Sciences Institute
6183A LSI
210 Washtenaw Ave.
Ann Arbor, MI 48109 -2216
Phone: 734-615-9915
Fax: 734-615-5493
Email: jnkim@umich.edu
Research:
Our lab studies the basic mechanisms and biological functions of microRNAs and other emerging classes of small RNAs. Using a wide-range of approaches, including genetics, biochemistry, and genomics, we want to understand the role of small, noncoding RNAs during development and differentiation.

David C. Kohrman
Associate Professor, Department of Otolaryngology/HNS -
Kresge Hearing Research Institute
Associate Professor, Department of Human Genetics
9301D MSRB III
1150 W. Medical Center Drive
Ann Arbor, MI 48109 -646
Phone: 734-763-9653
Fax: 
Email: dkohrman@umich.edu
Research:
Molecular genetics of inner ear structure and function, including analysis of the molecular basis of hearing loss and vestibular dysfunction in mice and humans.

Myron Levine
Professor Emeritus of Human Genetics
4909 Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor , MI 48109 -5618
Phone: 734-647-3149
Fax: 
Email: mylevine@umich.edu

Jun Li
Assistant Professor of Human Genetics
Research Assistant Professor, Center for Computational Medicine and Biology
5789 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-615-5754
Fax: 
Email: junzli@umich.edu
Research:
Genetic studies of complex human diseases, including psychiatric disorders,heart disease, and cancer, with emphases on genetic influence of gene expression, population structure, DNA copy number variation (eitherinherited or somatic), and application of next-generation sequencing methods to related problems.

Donna M. Martin
Associate Professor of Pediatrics
Associate Professor of Human Genetics
3520A MSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-647-4859
Fax: 734-763-9512
Email: donnamm@umich.edu
Research:
Molecular genetics of transcription factor mediated neuronal development; gene targeting; studies of human and mouse developmental disorders.

Monica Marvin
Genetic Counseling Assistant Program Director
4909 Buhl
1241 E. Catherine St.
Ann Arbor, MI 48109 -5618
Phone: 734-647-7399
Fax: 734-763-3784
Email: monicama@umich.edu
Research:
Understanding the applications and implications of the developing field of genomic medicine. We are looking at the practical and ethical consequences of translating genetic research into clinical practice.

Miriam H. Meisler
Professor of Human Genetics
4808 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-763-5546
Fax: 734-763-9691
Email: meislerm@umich.edu
Research:
We are interested in the molecular basis of inherited neurological
disorders, including epilepsy, ataxia, and peripheral neuropathy affecting
sensory and motor neurons. We use the approach of positional cloning
of mouse neurological mutants, followed by mutation screening of
appropriate human samples. Identification of each novel gene responsible
for disease opens opportunities for understanding new aspects of
cell biology and the systems effects of single gene perturbation.

John V. Moran
Professor of Human Genetics
Professor of Internal Medicine
Investigator, Howard Hughes Medical Institute
4728 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-615-0456
Fax: 734-763-3784
Email: moranj@umich.edu
Research:
Molecular analysis of human and mouse retrotransposons. Characterization of a novel retrotransposition mechanism. Studies of how transposable elements influence genomic diversity. Exploitation of human and mouse retrotransposons as genetic tools.

Gilbert S. Omenn
Professor of Internal Medicine
Professor of Human Genetics
Professor of Public Health
2017 Palmer Commons
100 Washtenaw Ave.
Ann Arbor, MI 48109 -2218
Phone: 734-763-7583
Fax: 734-615-6553
Email: gomenn@umich.edu
Research:
Cancer proteomics and chemoprevention; mechanisms of genetic predispositions to risks from environmental and occupational exposures especially for cancers and cardiovascular disease; pharmacogenetics and pharmacogenomics.

Elizabeth M. Petty
Associate Dean of Student Programs; Professor of Human Genetics; Professor of Internal Medicine; Medical Director, Genetic Counseling Training Program; Attending Physician, Genetics Clinic, Department of Internal Medicine
5220 MSRB III
1150 W. Medical Center Drive
Ann Arbor, MI 48109 -638
Phone: 734-763-2532
Fax: 734-647-7979
Email: epetty@umich.edu
Research:
Molecular genetic mechanisms underlying tumorigenesis with a focus on identifying and characterizing the roles of novel cancer genes; clinical genetics research projects related to the cost-effect and ethical application of molecular genetic tests in medicine.

Diane M. Robins
Professor of Human Genetics
Research Scientist for Reproductive Sciences Program
4706 Med Sci II
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-764-4563
Fax: 734-763-3784
Email: drobins@umich.edu
Research:
We study hormonally regulated gene transcription and androgen receptor function, at levels from the molecular to the organismal, focusing on mouse models of development and oncogenesis.

Noah A. Rosenberg
Associate Professor of Human Genetics
Associate Research Professor, Bioinformatics
Associate Research Professor, Life Sciences Institute
2017 Palmer Commons
100 Washtenaw Ave.
Ann Arbor, MI 48109 -2218
Phone: 734-615-5510
Fax: 
Email: rnoah@umich.edu
Research:
Mathematical models in genetics and evolution, human population genetics, statistical methods for inference of human genetic history, role of human genetic variation in disease-gene mapping, statistical genetics, genetic variation in pathogens, gene trees and species trees, phylogenetics

Jane L. Schuette
Clinical Instructor II, Human Genetics
Genetic Counselor, Department of Pediatrics and Communicable diseases
D5243 MPB
1100 W. Medical Center Drive
Ann Arbor, MI 48009 -5718
Phone: 734-764-0579
Fax: 
Email: janesc@umich.edu
Research:
Full-time clinical patient care and teaching. I will be involved in one of the genetic counseling graduate student's projects as primary mentor: assessment of clinical models and efficacy in delivery of genetic services to underserved populations.

JoAnn Sekiguchi
Assistant Professor of Human Genetics
Assistant Professor of Internal Medicine
2063 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-764-9514
Fax: 734-763-2162
Email: sekiguch@umich.edu
Research:
DNA repair and recombination. Molecular mechanisms of lymphocyte development. Molecular genetics of human immunodeficiencies and genomic instability cancer predisposition syndromes.

Charles F. Sing
Professor of Human Genetics
Photo by Nerissa Escalar, Mountain Sky Conference 2006
5928 Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-764-5492
Fax: 
Email: csing@umich.edu
Research:
Our research team is working to define the role of genetic variation in determining variation in health in the human population at large

Richard E. Tashian
Emeritus Professor of Human Genetics
4909 Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-647-3149
Fax: 734-763-3784
Email: retash@umich.edu

Wendy R. Uhlmann
Clinical Assistant Professor, Human Genetics
Genetic Counselor, Internal Medicine
300 North Ingalls Bldg, NI3 AO3
109 Zina Pitcher Place
Ann Arbor, MI 48109 -419
Phone: 734-763-2532
Fax: 734-763-7672
Email: wuhlmann@umich.edu

Tom E. Wilson
Associate Professor of Pathology
2065 BSRB
109 Zina Pitcher Place
Ann Arbor, MI 48109 -2200
Phone: 734-764-2212
Fax: 734-763-2162
Email: wilsonte@umich.edu

Beverly M. Yashar
Clinical Associate Professor of Human Genetics & Ophthalmology and Visual Sciences
Director Graduate Program Genetic Counseling
4924A Buhl
1241 E. Catherine St. SPC 5618
Ann Arbor, MI 48109 -5618
Phone: 734-763-2933
Fax: 734-763-3784
Email: yashar@umich.edu
Research:
Understanding the applications and implications of the developing field of genomic medicine. We are looking at the practical and ethical consequences of translating genetic research into clinical practice.