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Research Interest: The cooperation of miRNAs with tumor suppressive pathways in the development of cancer. |
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Research Interest: Applying coalescent theory to phylogenetics in order to model relationships between gene trees and species trees. |
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Research Interest: Determining how the RNA interference pathway regulates germline maintenance and genomic stability in C. elegans and mammalian tissue culture systems |
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Research Interest: I'm interested in retinal disease and am currently working with two mouse models of retinal degeneration. I'm trying to characterize the function of the gene mutated in each model. |
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Research Investigator |
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Research Interest: LINE-1 retrotransposition in embryonic stem cells. Epigenetic control of LINE-1 retrotransposition. |
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Research Interest: Identifying the downstream targets of Nrl and its implication in retina development and retina degeneration. |
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Research Interest: Anticopper treatment research on Wilson's disease, autoimmune diseases and tumors. |
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Research Interest: The impact of demography on gene-mapping in humans, human evolutionary genetics, theoretical population genetics, and domestication and founder events. |
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Research Interest: The molecular basis of inherited bleeding disorders including the characterization of a mouse model of Type 1 von Willebrand Disease and human studies in families with Familial ITP. |
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Research Investigator |
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Research Interest: The role of KRAB zinc finger repressors, Regulator of Sex-limitation 1 and 2, in sexually dimorphic liver gene expression and metabolic homeostasis. |
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Mirna Mustapha-Chaib
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Research Investigaor |
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Research Interest: Understanding thyroid hormone action in the developing auditory system and how unconventional myosin genes control development and function of the inner ear and/or vision. |
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Research Interest: The role of aging rod photoreceptors in mouse models of retinal degeneration. Also, the function of strawberry notch homolog-1 and its role in photoreceptor development. |
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Research Interest: Development of stochastic models of linkage disequilibrium for surveys of population genetic variation, such as mapping disease variants and assessing haplotype diversity. |
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Research Interest: Development of mouse and zebrafish models to map and clone modifier genes which influence the severity of blood clotting disorders. |
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Research Interest: Characterizing the residues and regions of the nuclease, Artemis, that are required for catalysis and regulation in DNA repair. |
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Research Interest: The impact of defects in components of the COPII machinery, including sec24a and sar1a, on the coagulation system as well as other aspects of normal mammalian physiology. |
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Research Interest: Degradation mechanisms and the molecular factors that control the expression of microRNA targets in C. elegans. |
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