News and Events
First demonstration of the poly(A) tail's key role in LINE-1 retrotransposition.
"In a new paper in Nature Communications, a team of scientists from the University of Michigan Medical School shows that the genetic material in female (but not male) cells makes tiny amounts of a special genetic material called RNA to make one of the two X chromosomes silent. They call this RNA XistAR."
The Sixth Annual Thomas D. Gelehrter Lecture in Medical Genetics was delivered on October 30, 2015 by Robert L. Nussbaum, M.D., Chief Medical Officer of Invitae, San Francisco, and former Chief of the Division of Genomic Medicine at the UCSF Program in Cardiovascular Genetics. To view the webcast, click here.
Robert L. Nussbaum, M.D., Chief Medical Officer of Invitae, a San Francisco genetics testing and information company, will deliver the Thomas D. Gelehrter Lecture in Medical Genetics on Friday, October 30, 2015 at 2:00 p.m. in the Kahn Auditorium, Biomedical Science Research Building (BSRB) on the University’s medical campus.
The event honors Thomas D. Gelehrter, M.D., former chair of the Department of Human Genetics at the University of Michigan and a leader in the human genetics community. Dr. Gelehrter, an internationally recognized expert, has promoted excellence in education, research, and patient care in medical genetics throughout his career and continues to raise awareness about the importance of medical genetics.
As a board-certified internist and medical geneticist, Dr. Nussbaum has dedicated his career to improving the care of adults and children with hereditary disorders. From 2006-2015, he was the Holly Smith Professor of Medicine at UCSF, Chief of the Division of Genomic Medicine, and led both the Cancer Risk Program at the Helen Diller Family Cancer Center and the UCSF Program in Cardiovascular Genetics. He was a member of the Executive Committee of the UCSF Institute for Human Genetics and directed the recently formed Genomic Medicine Initiative at UCSF. He came to UCSF in 2006 from the Division of Intramural Research of the National Human Genome Research Institute, NIH, where he served for 12 years as Chief of the Genetic Disease Research and Inherited Disease Research Branches. Before his time at NIH, he was an HHMI Associate Investigator, a professor in the Department of Genetics at the University of Pennsylvania, and an Attending Physician at Children’s Hospital of Philadelphia.
He received his training in medicine in the Harvard-MIT Joint Program in Health Technology, his internal medicine training at Barnes Hospital/Washington University, and his genetics training at Baylor College of Medicine. He is board certified in internal medicine, clinical genetics and clinical molecular genetics. Dr. Nussbaum directed the original research that led to the discovery of mutations in -synuclein in hereditary Parkinson disease in the mid 1990’s and has been studying its role in Parkinson disease ever since. For his work on Parkinson disease, he was awarded the Klaus Joachim Zülch-Prize for Neurological Research and the Jay Van Andel Award for Outstanding Achievement in Parkinson's Disease Research. He also carried out positional cloning and characterization of the gene mutated in Lowe syndrome that led to accurate biochemical and molecular genetic testing, for
He is the co-author of over 200 peer-reviewed publications in human genetics and co-author with Drs. Roderick M. McInnes and Huntington F. Willard of a popular textbook of human genetics, Thompson and Thompson's Genetics in Medicine. He has received numerous teaching awards from the University of Pennsylvania, the National Human Genome Research Institute and the University of California, San Francisco. Dr. Nussbaum is a Director and Treasurer of the American Board of Medical Genetics and Genomics and has served on the Board of Directors of the American College of Medical Genetics and Genomics and on the Board of the American Society of Human Genetics, where he also served as President in 2004. He was elected to the National Academy of Medicine in 2004 and the American Academy of Arts and Sciences in 2015.
Following the lecture, a reception will be held in the BSRB seminar rooms A-B-C.